Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.61 |
| ▸ | CASP6 | P55212 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213528 | 0.84 | NT5E (0.56) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL7890995 | 0.83 | NT5E (0.42) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL1413164 | 0.80 | NT5E (0.39) | NT5EALDH1A1HSD17B10 | |
| SCHEMBL5712067 | 0.79 | NT5E (0.78) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL2470360 | 0.78 | NT5E (0.61) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL7065409 | 0.78 | AURKA (0.39) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL27780861 | 0.77 | NT5E (0.75) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL6840785 | 0.76 | NT5E (1.00) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL150291 | 0.76 | NT5E (1.00) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL29415547 | 0.76 | NT5E (1.00) | NT5ECASP6ALDH1A1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599480-A1 | Compounds for the treatment of influenza | Universität Innsbruck (AT) | 2013-06-05 | — | — | EP | claimed |
| EP-0864614-A1 | Mixtures of azo dyes, azo dyes, process for their preparation and the use thereof | Ciba SC Holding AG (CH) | 1998-09-16 | — | — | EP | claimed |
| EP-2599480-A1 | Compounds for the treatment of influenza | Universität Innsbruck (AT) | 2013-06-05 | — | — | EP | disclosed |
| US-5997587-A | Azo dye mixtures, azo dyes, processes for their preparation, and their use | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0864614-A1 | Mixtures of azo dyes, azo dyes, process for their preparation and the use thereof | Ciba SC Holding AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| EP-0864614-A1 | Mixtures of azo dyes, azo dyes, process for their preparation and the use thereof | Ciba SC Holding AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4104270-A | Process for the manufacture of aromatic phosphonates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-01 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |