Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | PDE8A | O60658 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862449 | 0.80 | LRRK2 (0.34) | — | |
| SCHEMBL24704592 | 0.74 | TNIK (0.35) | — | |
| SCHEMBL22862567 | 0.73 | CSF1R (0.36) | HCAR1 | |
| SCHEMBL23530109 | 0.66 | HCAR1 (0.48) | HCAR1 | |
| SCHEMBL23529971 | 0.65 | HCAR1 (0.40) | HCAR1 | |
| SCHEMBL2192372 | 0.61 | HCAR1 (0.50) | HCAR1 | |
| SCHEMBL2195406 | 0.59 | HCAR1 (0.51) | HCAR1 | |
| SCHEMBL2195250 | 0.58 | HCAR1 (0.47) | HCAR1 | |
| SCHEMBL2195668 | 0.57 | HCAR1 (0.48) | HCAR1 | |
| SCHEMBL2195177 | 0.57 | HCAR1 (0.48) | HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389028-A1 | BAX INHIBITORS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389028-A1 | BAX INHIBITORS AND USES THEREOF | BAX, TMBIM6, BCL2 | HCAR1 4075/4885PDE8A 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.