Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470886 | 1.00 | PPP5C (0.31) | PPP5CPOLBNAAA | |
| SCHEMBL572647 | 0.75 | OPRM1 (0.33) | — | |
| SCHEMBL2439903 | 0.75 | — | — | |
| SCHEMBL572648 | 0.75 | OPRM1 (0.33) | — | |
| SCHEMBL8970567 | 0.74 | PPP5C (0.43) | PPP5CNAAA | |
| SCHEMBL8969446 | 0.73 | EPHX2 (0.45) | PPP5CNAAA | |
| SCHEMBL1842598 | 0.73 | L3MBTL1 (0.32) | — | |
| SCHEMBL1842599 | 0.73 | L3MBTL1 (0.32) | — | |
| SCHEMBL19834983 | 0.72 | ACE (0.33) | — | |
| SCHEMBL8970086 | 0.72 | EPHX2 (0.44) | PPP5CNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147836-A9 | COMBINATION THERAPIES USING ANTIBACTERIAL AMINOGLYCOSIDE COMPOUNDS | ACHAOGEN, INC. (US) | 2011-09-15 | — | — | WO | disclosed |