Ammonia Solution, Strong

SCHEMBL2470903

Cc1cn([C@H]2C[C@H](O)[C@@H](C(O)OP(O)(=S)O[C@]3(O)C[C@H](n4ccc(N)nc4=O)O[C@@H]3CO)O2)c(=O)[nH]c1=O.N

nearest known ligand 0.41

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY2	P41231	3/20	0.40

▸	P2RY4	P51582	3/20	0.40

▸	P2RY6	Q15077	2/20	0.40

▸	TK1	P04183	4/20	0.38

▸	POLB	P06746	2/20	0.36

▸	DTYMK	P23919	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Ammonia Solution, Strong SCHEMBL2470896	1.00	P2RY2 (0.40)	P2RY2P2RY4P2RY6TK1POLB
SCHEMBL2471150	0.99	P2RY2 (0.40)	P2RY2P2RY4P2RY6TK1POLB
SCHEMBL2471155	0.99	P2RY2 (0.40)	P2RY2P2RY4P2RY6TK1POLB
Ammonia Solution, Strong SCHEMBL2470891	0.91	P2RY2 (0.40)	P2RY2P2RY4P2RY6TK1POLB
Ammonia Solution, Strong SCHEMBL2469220	0.91	TK1 (0.45)	TK1POLB
Ammonia Solution, Strong SCHEMBL2469226	0.91	TK1 (0.45)	TK1POLB
Ammonia Solution, Strong SCHEMBL2470901	0.90	NT5E (0.39)	P2RY2P2RY4P2RY6TK1DTYMK
SCHEMBL16495058	0.90	P2RY2 (0.40)	P2RY2P2RY4P2RY6TK1POLB
SCHEMBL932884	0.90	TK1 (0.45)	TK1POLB
SCHEMBL932886	0.90	TK1 (0.45)	TK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2370451-A2	METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS	Chiralgen, Ltd. (JP)	2011-10-05	—	—	EP	disclosed
WO-2010064146-A2	METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS	CHIRALGEN, LTD. (JP)	2010-06-10	—	—	WO	disclosed