Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | DTYMK | P23919 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16495059 | 0.99 | NT5E (0.39) | NT5EP2RY2P2RY4P2RY6LMNA | |
| Ammonia Solution, Strong SCHEMBL2470903 | 0.90 | P2RY2 (0.40) | P2RY2P2RY4P2RY6DTYMKTK1 | |
| Ammonia Solution, Strong SCHEMBL2470896 | 0.90 | P2RY2 (0.40) | P2RY2P2RY4P2RY6DTYMKTK1 | |
| SCHEMBL2471155 | 0.90 | P2RY2 (0.40) | P2RY2P2RY4P2RY6DTYMKTK1 | |
| SCHEMBL2471150 | 0.90 | P2RY2 (0.40) | P2RY2P2RY4P2RY6DTYMKTK1 | |
| Ammonia Solution, Strong SCHEMBL2470891 | 0.81 | P2RY2 (0.40) | P2RY2P2RY4P2RY6DTYMKTK1 | |
| SCHEMBL16495058 | 0.81 | P2RY2 (0.40) | P2RY2P2RY4P2RY6DTYMKTK1 | |
| Ammonia Solution, Strong SCHEMBL2469220 | 0.80 | TK1 (0.45) | LMNAALBTK1 | |
| Ammonia Solution, Strong SCHEMBL2469226 | 0.80 | TK1 (0.45) | LMNAALBTK1 | |
| Ammonia Solution, Strong SCHEMBL2469221 | 0.80 | ALDH1A1 (0.39) | P2RY2LMNAALBTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370451-A2 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | Chiralgen, Ltd. (JP) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010064146-A2 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | CHIRALGEN, LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |