Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29300493 | 1.00 | ALDH1A1 (0.49) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL29300492 | 1.00 | ALDH1A1 (0.49) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL29300494 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL7127556 | 0.92 | ALDH1A1 (0.51) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL27331967 | 0.92 | ALDH1A1 (0.47) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL23153012 | 0.92 | ALDH1A1 (0.51) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL24709383 | 0.92 | ALDH1A1 (0.47) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL13474979 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL17971051 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL29302068 | 0.90 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM4ESMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129614-A1 | SOMATOSTATIN SUBTYPE-2 RECEPTOR (SST2R) TARGETED THERAPEUTICS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2022261221-A1 | NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |