Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31646761 | 0.94 | ALDH1A1 (0.47) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL15354487 | 0.92 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL29300492 | 0.92 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL20610685 | 0.92 | ALDH1A1 (0.46) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL24709151 | 0.92 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL24596998 | 0.92 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL29300493 | 0.92 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL13474979 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL29300494 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL15943369 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TDP1SMN1; SMN2KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722442-B1 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR INC (US) | 2003-01-15 | — | — | EP | disclosed |
| EP-0815091-B1 | POLYAZACYCLOALKANE COMPOUNDS | NYCOMED IMAGING AS (NO) | 2002-06-12 | — | — | EP | disclosed |
| US-5972307-A | ADMINISTERING TO HUMAN OR ANIMAL BODY AN EFFECTIVE AMOUNT OF A DIAGNOSTIC AGENT COMPRISES A METAL CHELATE OF A COMPOUND HAVING TWO MACROCYCLIC CHELANT GROUPS LINKED BY A BRIDGE CONTAINING ESTER OR AMIDE BOND | NYCOMED SALUTAR, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0815091-A1 | POLYAZACYCLOALKANE COMPOUNDS | NYCOMED IMAGING AS (NO) | 1998-01-07 | — | — | EP | disclosed |
| US-5705637-A | Polyazacycloalkane compounds | NYCOMED IMAGING AS (NO) | 1998-01-06 | — | — | US | disclosed |
| US-5677446-A | Polyazacycloalkane compounds | NYCOMED IMAGING AS (NO) | 1997-10-14 | — | — | US | disclosed |
| US-5650133-A | CHELATING AGENTS USEFUL IN DIAGNOSTIC AND THERAPEUTIC COMPOSITIONS | NYCOMED SALUTAR (US) | 1997-07-22 | — | — | US | disclosed |
| US-5631368-A | Polyazacycloalkane compounds | NYCOMED IMAGING AS (NO) | 1997-05-20 | — | — | US | disclosed |
| WO-1996028433-A1 | POLYAZACYCLOALKANE COMPOUNDS | NYCOMED IMAGING A.S (NO) | 1996-09-19 | — | — | WO | disclosed |
| EP-0722442-A1 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR, INC. (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009848-A2 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR, INC. (US) | 1995-04-13 | — | — | WO | disclosed |