Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 3/20 | 0.40 |
| ▸ | PNP | P00491 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890038 | 0.81 | CHRNB2 (0.53) | CHRNB2ADRA1DHTR1ECHRNA3ADRA1A | |
| SCHEMBL16870007 | 0.81 | CHRNB2 (0.57) | CHRNB2ADRA1DHTR1ECHRNA3ADRA1A | |
| SCHEMBL11261653 | 0.71 | PDE5A (0.46) | XDHPNP | |
| SCHEMBL12820649 | 0.70 | PNP (0.57) | XDHPNPALDH1A1HPGDKMT2A | |
| SCHEMBL10309075 | 0.70 | GAA (0.57) | CHRNB2ADRA1DHTR1ECHRNA3ADRA1A | |
| SCHEMBL8668761 | 0.70 | MAPT (0.43) | CHRNB2ADRA1DHTR1ECHRNA3ADRA1A | |
| SCHEMBL12820926 | 0.70 | TYMS (0.44) | XDHPNPTYMS | |
| SCHEMBL2069914 | 0.69 | TYMS (0.41) | XDHPNPTYMS | |
| SCHEMBL18520802 | 0.69 | TYMS (0.44) | XDHPNPTYMS | |
| SCHEMBL11233557 | 0.69 | PDE5A (0.40) | XDHPNPNPSR1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261030-A1 | OLIGONUCLEOTIDE ANALOGUE MODULATORS OF ONCOGENES | NEUBASE THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |