Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15812731 | 0.84 | CSNK1A1 (0.33) | CSNK1DCSNK1A1GSK3BCSNK1G2XDH | |
| SCHEMBL21263286 | 0.83 | PARP1 (0.34) | CSNK1DCSNK1A1GSK3BCSNK1G2XDH | |
| SCHEMBL25054312 | 0.83 | ALDH1A1 (0.38) | CSNK1DCSNK1A1GSK3BCSNK1G2XDH | |
| SCHEMBL24709841 | 0.83 | XDH (0.38) | CSNK1DCSNK1A1GSK3BCSNK1G2XDH | |
| SCHEMBL21879804 | 0.80 | CFB (0.38) | — | |
| SCHEMBL9754821 | 0.78 | ADORA1 (0.36) | ALDH1A1ADORA3 | |
| SCHEMBL5850166 | 0.75 | PARP1 (0.43) | ALDH1A1ADORA3PARP1 | |
| SCHEMBL21263175 | 0.72 | TYMS (0.38) | ALDH1A1ADORA3PARP1 | |
| SCHEMBL16801763 | 0.72 | NQO2 (0.42) | GSK3BALDH1A1ADORA3PARP1 | |
| SCHEMBL13544179 | 0.72 | ALDH1A1 (0.47) | ALDH1A1ADORA3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261221-A1 | NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |