Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.71 |
| ▸ | NPC1 | O15118 | 8/20 | 0.71 |
| ▸ | RAB9A | P51151 | 8/20 | 0.71 |
| ▸ | HPGD | P15428 | 8/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.71 |
| ▸ | TP53 | P04637 | 5/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | UTRN | P46939 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242803 | 0.76 | NPC1 (1.00) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2246140 | 0.76 | ALDH1A1 (0.77) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2240780 | 0.75 | CHIA (0.79) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2242920 | 0.75 | SMN1; SMN2 (0.80) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2243066 | 0.75 | CASP3 (0.74) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2245556 | 0.75 | UTRN (0.71) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2245009 | 0.74 | KDM4E (0.84) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2242342 | 0.74 | UTRN (0.69) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2242648 | 0.74 | KDM4E (0.71) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL2245196 | 0.74 | KDM4E (0.71) | ALDH1A1KDM4EHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | NEURALEXO, INC. | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | IRF3, IRF2BP2, STAT1 | ALDH1A1 4853/4885KDM4E 2942/4885HSD17B10 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.