Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.60 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920380 | 0.79 | SLC6A5 (0.86) | MAPTALDH1A1SLC6A9SLC6A5PAX8 | |
| SCHEMBL24710979 | 0.78 | KMT2A (0.72) | MAPTALDH1A1GAANPC1MEN1 | |
| SCHEMBL13687923 | 0.76 | SLC6A5 (0.84) | MAPTALDH1A1SLC6A9SLC6A5NPC1 | |
| SCHEMBL3919355 | 0.76 | SLC6A5 (1.00) | MAPTALDH1A1SLC6A9SLC6A5PAX8 | |
| SCHEMBL5047429 | 0.75 | SLC6A5 (0.81) | MAPTALDH1A1SLC6A9SLC6A5PAX8 | |
| SCHEMBL24710952 | 0.75 | MAPT (0.70) | MAPTALDH1A1GAANPC1POLB | |
| SCHEMBL24710998 | 0.75 | KMT2A (0.73) | MAPTALDH1A1GAANPC1POLB | |
| SCHEMBL3929976 | 0.74 | SLC6A9 (0.78) | SLC6A9SLC6A5PAX8 | |
| SCHEMBL13687894 | 0.74 | SLC6A5 (0.86) | MAPTALDH1A1SLC6A9SLC6A5PAX8 | |
| SCHEMBL24710857 | 0.73 | KMT2A (0.76) | MAPTALDH1A1GAANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | NEURALEXO, INC. | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | IRF3, IRF2BP2, STAT1 | MAPT 4038/4885ALDH1A1 4853/4885GAA 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.