⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391460 | 1.00 | — | — | |
| SCHEMBL4407762 | 1.00 | — | — | |
| SCHEMBL1063647 | 0.92 | — | — | |
| SCHEMBL28801700 | 0.90 | OPRM1 (0.48) | — | |
| SCHEMBL11298285 | 0.90 | OPRM1 (0.48) | — | |
| SCHEMBL1664514 | 0.90 | OPRM1 (0.48) | — | |
| SCHEMBL3326811 | 0.90 | OPRM1 (0.48) | — | |
| SCHEMBL3092823 | 0.90 | OPRM1 (0.48) | — | |
| SCHEMBL381494 | 0.90 | OPRM1 (0.48) | — | |
| SCHEMBL9828480 | 0.90 | OPRM1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284812-A1 | NOVEL SELECTIVE ANTIMICROBIAL FUSION PEPTIDES | Bombi Biomics BV (NL) | 2023-12-06 | — | — | EP | claimed |
| CN-106164087-B | Antimicrobial polypeptides and uses thereof | 莱顿大学学术医院以LUMC 的名义运作 | 2023-05-26 | — | — | CN | claimed |
| CN-105555290-B | Antimicrobial peptides | 莱顿大学学术医院以LUMC的名义运作 | 2021-11-09 | — | — | CN | claimed |
| CN-112358487-A | Lappaconitine derivative and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2021-02-12 | — | — | CN | claimed |
| EP-2994154-B1 | ANTIMICROBIAL PEPTIDE | ACADEMISCH ZIEKENHUIS LEIDEN (NL) | 2020-02-26 | — | — | EP | claimed |
| EP-3484908-A1 | NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM Chemicals Llc (US) | 2019-05-22 | — | — | EP | claimed |
| US-10130677-B2 | Antimicrobial peptide and uses thereof | ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) | 2018-11-20 | — | — | US | claimed |
| EP-3087092-B1 | ANTIMICROBIAL PEPTIDE AND USES THEREOF | ACADEMISCH ZIEKENHUIS LEIDEN (NL) | 2018-07-25 | — | — | EP | claimed |
| WO-2018013999-A1 | NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM CHEMICALS LLC (US) | 2018-01-18 | — | — | WO | claimed |
| US-9562085-B2 | Antimicrobial peptide | ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) | 2017-02-07 | — | — | US | claimed |
| WO-1996026950-A1 | INCREASED BIOAVAILABILITY OF BIOLOGICALLY ACTIVE COMPOUNDS BY LINKING TO POLYPYRROLECARBOXAMIDONAPHTHALENE DERIVATIVES | PHARMACIA S.P.A. (IT) | 1996-09-06 | — | — | WO | claimed |
| EP-0725648-A1 | HEPATOSELECTIVE PHARMACEUTICAL ACTIVES | THE UNITED MEDICAL AND DENTAL SCHOOLS OF GUY'S AND ST. THOMAS'S HOSPITALS (GB) | 1996-08-14 | — | — | EP | claimed |
| WO-1995005187-A1 | HEPATOSELECTIVE PHARMACEUTICAL ACTIVES | UNITED MEDICAL & DENTAL SCHOOLS OF GUY'S AND ST THOMAS' HOSPITALS (GB) | 1995-02-23 | — | — | WO | claimed |
| EP-0594656-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1994-05-04 | — | — | EP | claimed |
| WO-1993001166-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1993-01-21 | — | — | WO | claimed |
| US-5063109-A | Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents | ABBOTT LABORATORIES (US) | 1991-11-05 | — | — | US | claimed |
| US-5002883-A | Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents | ABBOTT LABORATORIES (US) | 1991-03-26 | — | — | US | claimed |
| EP-0303243-A2 | Use of atrial natriuretic factor (ANF), fragments and analogues thereof, for the treatment of cardiac disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-15 | — | — | EP | claimed |
| US-4680276-A | Metal polypeptides | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1987-07-14 | — | — | US | claimed |
| EP-0179332-A2 | ZNS-active peptides acting on the cholinergetic system | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-30 | — | — | EP | claimed |