Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | G6PD | P11413 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | MC4R | P32245 | 1/20 | 0.62 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.62 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24711005 | 0.87 | ALDH1A1 (0.74) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL24710979 | 0.80 | KMT2A (0.72) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL12653717 | 0.73 | ALDH1A1 (0.74) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL7156743 | 0.73 | SMN1; SMN2 (1.00) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL29967258 | 0.73 | NPY2R (0.75) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL15545383 | 0.73 | MAPT (0.68) | ALDH1A1MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL29967407 | 0.72 | NPY2R (0.74) | ALDH1A1MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL24629835 | 0.72 | MAPT (0.67) | ALDH1A1MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL13597049 | 0.71 | ALDH1A1 (0.77) | ALDH1A1MAPTHTTSMN1; SMN2NPSR1 | |
| SCHEMBL13602309 | 0.71 | KMT2A (0.64) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | NEURALEXO, INC. | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | IRF3, IRF2BP2, STAT1 | ALDH1A1 4853/4885KDM4E 2942/4885MAPT 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.