SCHEMBL29967258

SCHEMBL29967258

CCC(=O)N1CCN(c2ccc(NC(=O)Cc3ccccc3)cc2Cl)CC1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 4/20 0.75
▸ ALDH1A1 P00352 5/20 0.72
▸ TSHR P16473 3/20 0.72
▸ SMN1; SMN2 Q16637 3/20 0.72
▸ PKM P14618 1/20 0.72
▸ L3MBTL1 Q9Y468 1/20 0.72
▸ NPSR1 Q6W5P4 4/20 0.63
▸ MAPT P10636 3/20 0.63
▸ HTT P42858 3/20 0.63
▸ USP2 O75604 2/20 0.63
▸ KDM4E B2RXH2 1/20 0.63
▸ LMNA P02545 1/20 0.63
▸ TP53 P04637 1/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ HSD17B10 Q99714 1/20 0.63
▸ GAA P10253 1/20 0.62
▸ CYP2D6 P10635 1/20 0.58
▸ MITF O75030 1/20 0.57
▸ PAX8 Q06710 1/20 0.57
▸ MEN1 O00255 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29967407 0.86 NPY2R (0.74) NPY2RALDH1A1TSHRSMN1; SMN2PKM
SCHEMBL16688498 0.84 NPC1 (0.77) ALDH1A1TSHRSMN1; SMN2L3MBTL1NPSR1
SCHEMBL2527948 0.80 MAPT (0.65) NPY2RALDH1A1TSHRSMN1; SMN2NPSR1
SCHEMBL14791855 0.75 ALDH1A1 (0.57) ALDH1A1TSHRSMN1; SMN2PKML3MBTL1
SCHEMBL12781995 0.74 TSHR (0.70) ALDH1A1TSHRSMN1; SMN2PKML3MBTL1
SCHEMBL15757807 0.74 KMT2A (0.78) NPY2RALDH1A1L3MBTL1HTTKDM4E
SCHEMBL12781876 0.74 TSHR (0.61) ALDH1A1TSHRSMN1; SMN2PKML3MBTL1
SCHEMBL7157379 0.74 NPY2R (0.60) NPY2RALDH1A1SMN1; SMN2PKML3MBTL1
SCHEMBL6644998 0.74 NPY2R (0.60) NPY2RALDH1A1SMN1; SMN2PKML3MBTL1
SCHEMBL29873737 0.74 MAPT (0.72) NPY2RALDH1A1TSHRSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250098692-A1 GERMINATION/SPROUTING AND FRUIT RIPENING REGULATORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2025-03-27 — — US claimed
US-20220304322-A1 GERMINATION/SPROUTING AND FRUIT RIPENING REGULATORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2022-09-29 — — US claimed
WO-2022204503-A1 GERMINATION/SPROUTING AND FRUIT RIPENING REGULATORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2022-09-29 — — WO claimed
US-20250098692-A1 GERMINATION/SPROUTING AND FRUIT RIPENING REGULATORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2025-03-27 — — US disclosed
WO-2022204503-A1 GERMINATION/SPROUTING AND FRUIT RIPENING REGULATORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2022-09-29 — — WO disclosed
US-20220304322-A1 GERMINATION/SPROUTING AND FRUIT RIPENING REGULATORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2022-09-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250098692-A1 GERMINATION/SPROUTING AND FRUIT RIPENING REGULATORS BOLA2; BOLA2B, BROX, CDK5 NPY2R 1414/4885ALDH1A1 1637/4885TSHR 1519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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