Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21150507 | 0.85 | TSHR (0.39) | TSHRSMN1; SMN2PRKCBSLC6A9MAPT | |
| SCHEMBL15333158 | 0.82 | HRH3 (0.43) | TSHRSMN1; SMN2HRH3CYP2D6KCNH2 | |
| SCHEMBL15332364 | 0.82 | HRH3 (0.43) | TSHRSMN1; SMN2HRH3CYP2D6KCNH2 | |
| SCHEMBL12349924 | 0.82 | HRH3 (0.43) | TSHRSMN1; SMN2HRH3CYP2D6KCNH2 | |
| SCHEMBL20008992 | 0.80 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2PRKCBSLC6A9MAPT | |
| SCHEMBL20009022 | 0.80 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2PRKCBSLC6A9MAPT | |
| SCHEMBL16869402 | 0.80 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2PRKCBSLC6A9MAPT | |
| SCHEMBL24711535 | 0.79 | SMN1; SMN2 (0.37) | TSHRSMN1; SMN2PRKCBSLC6A9MAPT | |
| SCHEMBL23876806 | 0.79 | PIK3CD (0.40) | TSHRSMN1; SMN2PIK3CDPRKCBSLC6A9 | |
| SCHEMBL24890702 | 0.77 | TSHR (0.64) | TSHRPIK3CDCHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261243-A1 | COMBINATION THERAPIES WITH SETD2 INHIBITORS | Epizyme, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |