Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316674 | 0.84 | MEN1 (0.47) | ALDH1A1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL2073087 | 0.78 | MEN1 (0.52) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL12809838 | 0.78 | MEN1 (0.52) | ALDH1A1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL24584923 | 0.78 | TXNRD1 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| Acetic Acid SCHEMBL10842577 | 0.76 | HDAC8 (0.60) | HDAC8HDAC6MEN1KMT2ATDP1 | |
| SCHEMBL156664 | 0.74 | MEN1 (0.56) | ALDH1A1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL1913535 | 0.74 | MEN1 (0.56) | ALDH1A1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL5181873 | 0.74 | THRB (0.56) | ALDH1A1HDAC8HDAC6MEN1KMT2A | |
| Acetone SCHEMBL8184954 | 0.74 | HDAC8 (0.58) | HDAC8HDAC6MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL9144926 | 0.73 | MEN1 (0.47) | ALDH1A1HDAC8MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232195-A2 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-11-03 | — | — | WO | disclosed |