Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 7/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.63 |
| ▸ | MEN1 | O00255 | 9/20 | 0.63 |
| ▸ | USP2 | O75604 | 8/20 | 0.63 |
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | RGS12 | O14924 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28798795 | 0.89 | KEAP1 (0.64) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL13964866 | 0.82 | USP2 (0.70) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL9437193 | 0.81 | KMT2A (0.78) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL3470386 | 0.81 | MEN1 (0.66) | KMT2AMEN1CYP1B1MAPTALDH1A1 | |
| SCHEMBL12660518 | 0.80 | KMT2A (0.67) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL13964867 | 0.80 | KMT2A (0.67) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL29086656 | 0.79 | HEXA (0.67) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL3891083 | 0.79 | KMT2A (0.74) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL1477933 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL29441539 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4102227-A1 | NOVEL COMPOUND TO BE PHOTO-CROSSLINKED BY VISIBLE LIGHT, AND USE THEREOF | Seoul National University R & DB Foundation (KR) | 2022-12-14 | — | — | EP | disclosed |