Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25041792 | 0.77 | KMT2A (0.44) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL4672433 | 0.73 | GAA (0.52) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL13073621 | 0.69 | ALDH1A1 (0.49) | GAAALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10272910 | 0.69 | PDE10A (0.53) | GAAALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL19526989 | 0.69 | MAPT (0.46) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL17667898 | 0.68 | KDM4E (0.41) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL14553999 | 0.68 | SORD (0.54) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL17226866 | 0.67 | ALDH1A1 (0.51) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL16840723 | 0.67 | KDM4E (0.56) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL27657858 | 0.67 | POLB (0.44) | GAAALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |