Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14117235 | 0.84 | HPGD (0.47) | HPGDSMN1; SMN2LRRK2SLC13A5 | |
| SCHEMBL5942718 | 0.82 | GRM2 (0.38) | HPGDSMN1; SMN2MTNR1ACDC7DBF4 | |
| SCHEMBL18589185 | 0.82 | MEN1 (0.42) | IDO1MTNR1ALRRK2CDC7DBF4 | |
| SCHEMBL23219832 | 0.80 | HPGD (0.35) | IDO1HPGDSMN1; SMN2MTNR1ASLC13A5 | |
| SCHEMBL24344519 | 0.78 | AURKA (0.38) | HPGDSMN1; SMN2MTNR1ARPS6KA5NOS3 | |
| SCHEMBL24344266 | 0.78 | HPGD (0.46) | HPGDSMN1; SMN2MTNR1ACDC7DBF4 | |
| SCHEMBL1135203 | 0.78 | LMNA (0.40) | HPGDSMN1; SMN2 | |
| SCHEMBL12052563 | 0.77 | LRRK2 (0.33) | HPGDSMN1; SMN2LRRK2ACSS2 | |
| SCHEMBL11965050 | 0.75 | FFAR1 (0.37) | HPGDSMN1; SMN2RPS6KA5NOS3NOS2 | |
| SCHEMBL439658 | 0.75 | NFE2L2 (0.36) | IDO1NFE2L2APLNRCCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |