SCHEMBL24713624

SCHEMBL24713624

CC1(N)CC(c2ccccc2)=Cc2ccsc21

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
RAB9A P51151 1/20 0.39
HPGD P15428 1/20 0.37
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22891232 0.84 NPC1 (0.41) NPC1RAB9AHPGDALDH1A1LMNA
SCHEMBL22415118 0.72
SCHEMBL23938624 0.70 NPC1 (0.39) NPC1RAB9AHPGDALDH1A1LMNA
SCHEMBL28874436 0.66 NPC1 (0.37) NPC1RAB9AHPGDALDH1A1LMNA
SCHEMBL22475295 0.64 RARA (0.36) HPGDALDH1A1LMNA
SCHEMBL21242653 0.63 NPC1 (0.43) NPC1RAB9AHPGDALDH1A1LMNA
SCHEMBL23766444 0.62 CYP11B1 (0.33) ALDH1A1LMNA
SCHEMBL24770458 0.58 KDM1A (0.35)
SCHEMBL23790984 0.56 NPC1 (0.41) NPC1RAB9AHPGDALDH1A1LMNA
SCHEMBL12200085 0.56 KDM1A (0.39) NPC1RAB9AHPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4101908-A1 COMPOSITION, LAYER INCLUDING THE COMPOSITION, LIGHT-EMITTING DEVICE INCLUDING THE COMPOSITION, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2022-12-14 EP disclosed
EP-4102590-A2 COMPOSITION, LAYER INCLUDING THE COMPOSITION, LIGHT-EMITTING DEVICE INCLUDING THE COMPOSITION, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2022-12-14 EP disclosed