Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 9/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | KIF5B | P33176 | 6/20 | 0.53 |
| ▸ | KDR | P35968 | 5/20 | 0.53 |
| ▸ | BRAF | P15056 | 8/20 | 0.53 |
| ▸ | RAF1 | P04049 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168733 | 0.88 | EGFR (0.54) | RETEGFRKIF5BKDR | |
| SCHEMBL30820451 | 0.88 | EGFR (0.54) | RETEGFRKIF5BKDR | |
| SCHEMBL27151646 | 0.84 | EGFR (0.54) | RETEGFRKDR | |
| SCHEMBL30820598 | 0.84 | ABCG2 (0.59) | RETEGFRKIF5BKDRBRAF | |
| SCHEMBL24714641 | 0.83 | EGFR (0.56) | RETEGFRKIF5BKDR | |
| SCHEMBL24713876 | 0.83 | EGFR (0.56) | RETEGFRKIF5BKDR | |
| SCHEMBL30822096 | 0.82 | EGFR (0.57) | EGFRKDR | |
| SCHEMBL27140470 | 0.82 | EGFR (0.57) | EGFRKDR | |
| SCHEMBL24713875 | 0.82 | EGFR (0.55) | RETEGFRKIF5BKDR | |
| SCHEMBL24714079 | 0.82 | EGFR (0.47) | RETEGFRKIF5BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |