Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.54 |
| ▸ | RET | P07949 | 6/20 | 0.47 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | KIF5B | P33176 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30820451 | 1.00 | EGFR (0.54) | EGFRRETKDRMAPK1FLT1 | |
| SCHEMBL24714014 | 0.88 | RET (0.55) | EGFRRETKDRKIF5B | |
| SCHEMBL27151646 | 0.84 | EGFR (0.54) | EGFRRETKDRMAPK1HTT | |
| SCHEMBL30820598 | 0.84 | ABCG2 (0.59) | EGFRRETKDRMAPK1FLT1 | |
| SCHEMBL24714641 | 0.83 | EGFR (0.56) | EGFRRETKDRMAPK1FLT1 | |
| SCHEMBL24713876 | 0.83 | EGFR (0.56) | EGFRRETKDRMAPK1FLT1 | |
| SCHEMBL24713875 | 0.82 | EGFR (0.55) | EGFRRETKDRMAPK1FLT1 | |
| SCHEMBL24714943 | 0.81 | EGFR (0.56) | EGFRRETKDRMAPK1FLT1 | |
| SCHEMBL30822096 | 0.81 | EGFR (0.57) | EGFRKDR | |
| SCHEMBL24714929 | 0.81 | EGFR (0.54) | EGFRRETKDRMAPK1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693505-A | Heteroaryl derivative compounds and uses thereof | 沃若诺伊公司 | 2024-03-12 | — | — | CN | disclosed |