Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713929 | 0.83 | SMN1; SMN2 (0.57) | MEN1KMT2ASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL24713219 | 0.81 | P2RX7 (0.48) | SMN1; SMN2LMNAANO1HPGDHTT | |
| SCHEMBL30296102 | 0.80 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL23362766 | 0.80 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL25144074 | 0.79 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL6343545 | 0.78 | HSD17B10 (0.70) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL29431167 | 0.78 | HSD17B10 (0.70) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL10864128 | 0.78 | CYP3A4 (0.62) | MEN1KMT2ASMN1; SMN2HSD17B10HPGD | |
| SCHEMBL23619857 | 0.78 | P2RX7 (0.50) | — | |
| SCHEMBL25213857 | 0.77 | GAA (0.52) | SMN1; SMN2LMNAHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |