Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.52 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.47 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 16/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27139860 | 0.94 | EGFR (0.53) | EGFRERBB3DUS2KDR | |
| SCHEMBL27136337 | 0.90 | EGFR (0.51) | EGFRERBB3DUS2KDR | |
| SCHEMBL24713933 | 0.88 | EGFR (0.51) | EGFRERBB3DUS2KDR | |
| SCHEMBL30822153 | 0.87 | EGFR (0.49) | EGFRERBB3DUS2KDR | |
| SCHEMBL24714506 | 0.87 | EGFR (0.49) | EGFRERBB3DUS2KDR | |
| SCHEMBL24714950 | 0.85 | EGFR (0.55) | EGFRERBB3DUS2KDR | |
| SCHEMBL30030882 | 0.85 | EGFR (0.55) | EGFRERBB3DUS2KDR | |
| SCHEMBL24714969 | 0.85 | EGFR (0.63) | EGFRERBB3DUS2KDR | |
| SCHEMBL24714736 | 0.78 | EGFR (0.48) | EGFRKDR | |
| SCHEMBL24714738 | 0.78 | EGFR (0.49) | EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |