Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.55 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.46 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.45 |
| ▸ | KIT | P10721 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.45 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.45 |
| ▸ | CIT | O14578 | 1/20 | 0.45 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | STK17B | O94768 | 1/20 | 0.45 |
| ▸ | STK10 | O94804 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30030882 | 1.00 | EGFR (0.55) | EGFRKDRERBB3DUS2ERBB2 | |
| SCHEMBL27139860 | 0.86 | EGFR (0.53) | EGFRKDRERBB3DUS2 | |
| SCHEMBL24713933 | 0.86 | EGFR (0.51) | EGFRKDRERBB3DUS2 | |
| SCHEMBL30822153 | 0.86 | EGFR (0.49) | EGFRKDRERBB3DUS2ERBB2 | |
| SCHEMBL24714506 | 0.86 | EGFR (0.49) | EGFRKDRERBB3DUS2ERBB2 | |
| SCHEMBL24714723 | 0.85 | EGFR (0.52) | EGFRKDRERBB3DUS2 | |
| SCHEMBL27136337 | 0.85 | EGFR (0.51) | EGFRKDRERBB3DUS2 | |
| SCHEMBL24714969 | 0.83 | EGFR (0.63) | EGFRKDRERBB3DUS2SRC | |
| SCHEMBL30031056 | 0.79 | EGFR (0.60) | EGFRERBB2SRCERBB4GAK | |
| SCHEMBL24714972 | 0.79 | EGFR (0.60) | EGFRERBB2SRCERBB4GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328222-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | Voronoi Inc. (KR) | 2024-02-28 | — | — | EP | claimed |
| EP-4328222-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | Voronoi Inc. (KR) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |