Albendazole

Albendazole

SCHEMBL247151

CCCSc1ccc2nc(NC(=O)OC)[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 1.00
CYP1A2 P05177 6/20 1.00
MAPK1 P28482 4/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
NPSR1 Q6W5P4 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
HPGD P15428 2/20 1.00
TP53 P04637 2/20 1.00
KCNH2 Q12809 1/20 1.00
HIF1A Q16665 5/20 0.67
CYP2C19 P33261 1/20 0.67
NR1I2 O75469 1/20 0.66
MAPK14 Q16539 1/20 0.66
TUBB4A P04350 6/20 0.63
TUBB P07437 6/20 0.63
TUBA3C P0DPH7 6/20 0.63
TUBA1B P68363 6/20 0.63
TUBA4A P68366 6/20 0.63
TUBB4B P68371 6/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Albendazole SCHEMBL31704207 1.00 LMNA (1.00) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
Albendazole SCHEMBL5502364 0.96 LMNA (0.91) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
Albendazole SCHEMBL29612190 0.92 LMNA (0.85) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
SCHEMBL7258034 0.91 LMNA (0.83) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
Albendazole SCHEMBL44682 0.91 LMNA (0.83) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
Albendazole SCHEMBL7969988 0.91 LMNA (0.83) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
Albendazole SCHEMBL29409236 0.91 LMNA (0.83) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
Albendazole SCHEMBL28582887 0.89 LMNA (0.81) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
Albendazole SCHEMBL28958723 0.89 LMNA (0.81) LMNACYP1A2MAPK1SMN1; SMN2NPSR1
SCHEMBL18142126 0.88 LMNA (0.78) LMNACYP1A2MAPK1SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3046 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382291-A1 SUBSTITUTED PYRROLO[2,3-b]PYRIDINES FOR SUPPRESSING TOXIC ENDOPLASMIC RETICULUM STRESS UNIV COLUMBIA (US) 2025-12-18 US claimed
US-20250352518-A1 A BENZIMIDAZOLE COMPOUND WITH ANTIHELMINTHIC ACTIVITY FOR USE IN REVERSING, ARRESTING OR SLOWING DOWN CELLULAR AGEING IN A VERTEBRATE SUBJECT RAVAN BIO LIMITED (GB) 2025-11-20 US claimed
CN-119876411-A Haemonchus contortus albendazole drug resistance detection primer, probe and detection method 内蒙古农业大学 2025-04-25 CN claimed
EP-4539808-A1 A BENZIMIDAZOLE COMPOUND WITH ANTIHELMINTHIC ACTIVITY FOR USE IN REVERSING, ARRESTING OR SLOWING DOWN CELLULAR AGEING IN A VERTEBRATE SUBJECT Ravan Bio Limited (GB) 2025-04-23 EP claimed
CN-119351090-A Fluorescent probe synthesized by using expired medicine and preparation method and application thereof 昆明市延安医院(昆明市干部疗养院) 2025-01-24 CN claimed
WO-2024264013-A1 BIOAVAILABILITY ENHANCING IONIC LIQUID FORMULATIONS AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2024-12-26 WO claimed
EP-4473964-A1 COMPOSITION COMPRISING BETA BLOCKER AND CHOLINESTERASE INHIBITOR FOR TREATMENT OF NEURODEGENERATIVE DISEASE Dr.Noah Biotech Inc. (KR) 2024-12-11 EP claimed
US-20240390364-A1 Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions REID CHRISTOPHER BRIAN (US) 2024-11-28 US claimed
CN-118453635-B Albendazole ivermectin nano-preparation and preparation method thereof 中国农业科学院农业环境与可持续发展研究所 2024-11-01 CN claimed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO claimed
US-5169846-A Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators CROOKS MICHAEL J (AU) 1992-12-08 US claimed
EP-0427582-A2 Non-aqueous micellar solutions of various drugs Crooks, Michael John (AU) 1991-05-15 EP claimed
CN-86108096-A Novel stabilizing benzimidazole derivative 1987-07-08 CN claimed
US-4643893-A FOR ADMINISTERING MEDICINE TO ANIMAL RUMEN C.R.B. VIRBAC S.A. (FR) 1987-02-17 US claimed
EP-0146573-A1 PHARMACEUTICAL COMPOSITIONS WITH ANTHELMINTIC ACTIVITY, DOSAGE UNITS THEREOF AND METHOD FOR TREATING HELMINTHIASIS IN ANIMALS HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-03 EP claimed
WO-1984004677-A1 PHARMACEUTICAL COMPOSITIONS WITH ANTHELMINTIC ACTIVITY, DOSAGE UNITS THEREOF AND METHOD FOR TREATING HELMINTHIASIS IN ANIMALS HOECHST AG (DE) 1984-12-06 WO claimed
EP-0059074-B1 ANTHELMINTIC COMPOSITION AND THE USE THEREOF SANKYO COMPANY LIMITED (JP) 1984-10-10 EP claimed
US-4468390-A Anthelmintic composition and the use thereof SANKYO COMPANY, LIMITED (JP) 1984-08-28 US claimed
EP-0093497-A2 Anthelmintic treatment SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1983-11-09 EP claimed
EP-0059074-A1 Anthelmintic composition and the use thereof SANKYO COMPANY LIMITED (JP) 1982-09-01 EP claimed