Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 14/20 | 0.70 |
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.58 |
| ▸ | INSR | P06213 | 2/20 | 0.58 |
| ▸ | IGF1R | P08069 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29869091 | 1.00 | MAP4K1 (0.70) | MAP4K1EGFRALKINSRIGF1R | |
| SCHEMBL24716025 | 0.88 | MAP4K1 (0.71) | MAP4K1EGFR | |
| SCHEMBL24716363 | 0.87 | MAP4K1 (0.61) | MAP4K1ALK | |
| SCHEMBL24715919 | 0.87 | MAP4K1 (0.53) | MAP4K1ALK | |
| SCHEMBL29102658 | 0.86 | MAP4K1 (0.52) | MAP4K1ALK | |
| SCHEMBL24039985 | 0.85 | MAP4K1 (0.84) | MAP4K1EGFRALKINSRIGF1R | |
| SCHEMBL20214787 | 0.85 | MAP4K1 (0.84) | MAP4K1EGFRALKINSRIGF1R | |
| SCHEMBL24716029 | 0.85 | ALK (0.58) | MAP4K1ALKINSRIGF1R | |
| SCHEMBL24716376 | 0.85 | MAP4K1 (0.61) | MAP4K1EGFRALKINSR | |
| SCHEMBL24716361 | 0.85 | MAP4K1 (0.55) | MAP4K1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214008-A1 | HIGHLY ACTIVE HPK1 KINASE INHIBITOR | 杭州阿诺生物医药科技有限公司 | 2022-10-13 | — | — | WO | disclosed |