Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.63 |
| ▸ | INSR | P06213 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24716293 | 0.90 | ALK (0.71) | ALKINSR | |
| SCHEMBL29869922 | 0.90 | ALK (0.71) | ALKINSR | |
| SCHEMBL24716297 | 0.81 | ALK (0.57) | ALK | |
| SCHEMBL29869266 | 0.81 | ALK (0.57) | ALK | |
| SCHEMBL24716029 | 0.81 | ALK (0.58) | ALKINSR | |
| SCHEMBL24716011 | 0.80 | ALK (0.56) | ALK | |
| SCHEMBL24716362 | 0.79 | AXL (0.71) | ALKINSR | |
| SCHEMBL24716366 | 0.79 | ALK (0.60) | ALKINSR | |
| SCHEMBL29869267 | 0.79 | ALK (0.60) | ALKINSR | |
| SCHEMBL18759929 | 0.77 | ALK (1.00) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214008-A1 | HIGHLY ACTIVE HPK1 KINASE INHIBITOR | 杭州阿诺生物医药科技有限公司 | 2022-10-13 | — | — | WO | disclosed |