Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24717022 | 0.82 | HDAC1 (0.41) | HDAC1HDAC8HDAC6HDAC5BPTF | |
| SCHEMBL24717003 | 0.79 | HDAC1 (0.40) | HDAC1HDAC8HDAC6HDAC5BPTF | |
| SCHEMBL24717012 | 0.73 | BPTF (0.34) | HDAC1HDAC8HDAC6HDAC5BPTF | |
| SCHEMBL9892990 | 0.65 | ABL1 (0.44) | HDAC1HDAC8HDAC6HDAC5BPTF | |
| SCHEMBL15133232 | 0.65 | — | — | |
| SCHEMBL22854290 | 0.63 | ALDH1A1 (0.39) | HDAC1HDAC8HDAC6HDAC5NOTUM | |
| SCHEMBL24415608 | 0.63 | SLC6A2 (0.41) | BPTFTSHR | |
| SCHEMBL20672079 | 0.62 | — | — | |
| SCHEMBL9891772 | 0.62 | BPTF (0.39) | HDAC1HDAC8HDAC6HDAC5BPTF | |
| SCHEMBL9891746 | 0.62 | CNR2 (0.45) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257894-A1 | P300 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 贝达药业股份有限公司 | 2022-12-15 | — | — | WO | disclosed |