Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24717007 | 0.82 | HDAC1 (0.43) | HDAC1HDAC8HDAC6HDAC5BPTF | |
| SCHEMBL29348974 | 0.77 | MEN1 (0.38) | TSHRNOTUMCCR1CCR2 | |
| SCHEMBL9892990 | 0.77 | ABL1 (0.44) | HDAC1HDAC8HDAC6HDAC5BPTF | |
| SCHEMBL24415608 | 0.75 | SLC6A2 (0.41) | BPTFTSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22854290 | 0.75 | ALDH1A1 (0.39) | HDAC1HDAC8HDAC6HDAC5NOTUM | |
| SCHEMBL17689121 | 0.72 | HDAC6 (0.40) | HDAC1HDAC8HDAC6HDAC5NOTUM | |
| SCHEMBL15713541 | 0.71 | HDAC6 (0.39) | HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL17688867 | 0.70 | HDAC6 (0.40) | HDAC1HDAC8HDAC6HDAC5NOTUM | |
| SCHEMBL21522934 | 0.69 | NOTUM (0.32) | NOTUM | |
| SCHEMBL30888993 | 0.69 | NOTUM (0.32) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257894-A1 | P300 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 贝达药业股份有限公司 | 2022-12-15 | — | — | WO | disclosed |