Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197793 | 0.79 | NOTUM (0.43) | KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25146433 | 0.78 | CHRNB2 (0.35) | MAPTALDH1A1TSHRNPSR1PKM | |
| SCHEMBL18129723 | 0.77 | RYR2 (0.34) | ALDH1A1NPSR1 | |
| SCHEMBL12883921 | 0.74 | LMNA (0.42) | KMT2AMAPTALDH1A1TSHRKIF11 | |
| SCHEMBL25802121 | 0.73 | ESR1 (0.42) | — | |
| SCHEMBL19981883 | 0.73 | DPP4 (0.44) | — | |
| SCHEMBL2251926 | 0.71 | MAPT (0.48) | KMT2AMAPTALDH1A1TSHRMEN1 | |
| SCHEMBL16809856 | 0.70 | MAPT (0.41) | KMT2AMAPTALDH1A1TSHRCCNT1 | |
| SCHEMBL12519920 | 0.70 | ESR2 (0.47) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL10142910 | 0.69 | MAPT (0.39) | KMT2AMAPTALDH1A1TSHRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257894-A1 | P300 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 贝达药业股份有限公司 | 2022-12-15 | — | — | WO | disclosed |