Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22134171 | 0.92 | TSHR (0.45) | TSHRCNR2P2RX7BPTFHDAC1 | |
| SCHEMBL20093855 | 0.92 | TSHR (0.45) | TSHRCNR2P2RX7BPTFHDAC1 | |
| SCHEMBL24717146 | 0.83 | TSHR (0.40) | TSHRCNR2CREBBPEP300CCR1 | |
| SCHEMBL24717148 | 0.83 | TSHR (0.40) | TSHRCNR2CREBBPEP300CCR1 | |
| SCHEMBL24415608 | 0.78 | SLC6A2 (0.41) | TSHRCREBBPEP300CCR1CCR2 | |
| SCHEMBL9106744 | 0.78 | TSHR (0.52) | TSHRCNR2P2RX7BPTFHDAC1 | |
| SCHEMBL9106736 | 0.78 | TSHR (0.52) | TSHRCNR2P2RX7BPTFHDAC1 | |
| SCHEMBL24416847 | 0.75 | BPTF (0.40) | TSHRCNR2CREBBPEP300CCR1 | |
| SCHEMBL24415451 | 0.75 | CREBBP (0.38) | TSHRCNR2CREBBPEP300CCR1 | |
| SCHEMBL24717306 | 0.75 | BPTF (0.40) | TSHRCNR2CREBBPEP300CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257894-A1 | P300 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 贝达药业股份有限公司 | 2022-12-15 | — | — | WO | disclosed |