Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 4/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24416847 | 1.00 | BPTF (0.40) | BPTFHDAC1HDAC8HDAC6CREBBP | |
| SCHEMBL24415452 | 0.86 | LMNA (0.43) | TSHR | |
| SCHEMBL24415608 | 0.81 | SLC6A2 (0.41) | BPTFCREBBPTSHREP300BRD4 | |
| SCHEMBL24415451 | 0.78 | CREBBP (0.38) | BPTFHDAC1HDAC8HDAC6CREBBP | |
| SCHEMBL24717149 | 0.75 | TSHR (0.43) | BPTFHDAC1HDAC8HDAC6CREBBP | |
| SCHEMBL9893023 | 0.75 | PER2 (0.46) | TSHRPER2CNR2 | |
| SCHEMBL9892990 | 0.75 | ABL1 (0.44) | BPTFHDAC1HDAC8HDAC6TSHR | |
| SCHEMBL24717148 | 0.75 | TSHR (0.40) | BPTFHDAC1HDAC8HDAC6CREBBP | |
| SCHEMBL24717146 | 0.72 | TSHR (0.40) | BPTFHDAC1HDAC8HDAC6CREBBP | |
| SCHEMBL24717003 | 0.71 | HDAC1 (0.40) | BPTFHDAC1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257894-A1 | P300 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 贝达药业股份有限公司 | 2022-12-15 | — | — | WO | disclosed |