Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471322 | 0.91 | AVPR1A (0.33) | — | |
| SCHEMBL2472822 | 0.90 | — | — | |
| SCHEMBL2474676 | 0.88 | AVPR1A (0.31) | — | |
| SCHEMBL2474258 | 0.87 | — | — | |
| SCHEMBL2472708 | 0.87 | CYP11B2 (0.33) | CYP11B2 | |
| SCHEMBL2564790 | 0.85 | CYP11B2 (0.32) | CYP11B2 | |
| SCHEMBL2475001 | 0.85 | AADAT (0.32) | — | |
| SCHEMBL2474345 | 0.84 | — | — | |
| SCHEMBL2340647 | 0.82 | — | — | |
| SCHEMBL2559875 | 0.81 | CYP11B2 (0.38) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370441-A1 | ARYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES FOR USE AS VASOPRESSIN VIA RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060836-A1 | ARYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES FOR USE AS VASOPRESSIN VIA RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-03 | — | — | WO | disclosed |