Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 14/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470438 | 0.86 | DPP4 (0.51) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL2472452 | 0.84 | DPP4 (0.70) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL2469613 | 0.81 | DPP4 (0.71) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL8261829 | 0.81 | DPP4 (0.71) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL13342410 | 0.81 | DPP4 (0.71) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL3532200 | 0.80 | DPP4 (0.58) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL8259829 | 0.69 | DPP4 (0.71) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL13342399 | 0.69 | DPP4 (0.71) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL2471779 | 0.69 | DPP4 (0.33) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL840027 | 0.68 | KDM4E (0.39) | DPP4DPP7DPP9KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819674-B1 | FUSED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK SHARP & DOHME (US) | 2011-10-05 | — | — | EP | disclosed |