Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471875 | 1.00 | OPRK1 (0.40) | OPRK1HDAC6HDAC1TPSAB1PIN1 | |
| SCHEMBL19059441 | 0.86 | HDAC6 (0.49) | HDAC6HDAC1MEN1KMT2A | |
| SCHEMBL9847306 | 0.84 | MEN1 (0.34) | HDAC6HDAC1MEN1KMT2A | |
| SCHEMBL29002722 | 0.83 | HDAC6 (0.42) | HDAC6HDAC1MEN1ALDH1A1LMNA | |
| SCHEMBL12329492 | 0.82 | OPRK1 (0.49) | OPRK1HDAC6HDAC1TPSAB1MEN1 | |
| SCHEMBL12198404 | 0.82 | OPRK1 (0.48) | OPRK1MEN1ALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL3794525 | 0.81 | HDAC6 (0.41) | HDAC6HDAC1TPSAB1MEN1ALDH1A1 | |
| SCHEMBL5808669 | 0.81 | HDAC6 (0.39) | HDAC6HDAC1ALDH1A1 | |
| SCHEMBL5808668 | 0.81 | HDAC6 (0.39) | HDAC6HDAC1ALDH1A1 | |
| SCHEMBL19451083 | 0.81 | HDAC6 (0.48) | HDAC6HDAC1TPSAB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| WO-2011107948-A2 | LIGANDS OF INSULIN DEGRADING ENZYME AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2011-09-09 | — | — | WO | disclosed |