Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24384574 | 0.86 | TLR7 (0.38) | TLR7TLR8 | |
| SCHEMBL29492937 | 0.79 | TLR8 (0.65) | TLR7TLR8 | |
| SCHEMBL22826036 | 0.79 | TLR8 (0.65) | TLR7TLR8 | |
| SCHEMBL24384588 | 0.79 | TLR8 (0.65) | TLR7TLR8 | |
| SCHEMBL22825827 | 0.78 | KCNH2 (0.41) | TLR7TLR8 | |
| SCHEMBL22825626 | 0.78 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL13975904 | 0.74 | CYP2D6 (0.61) | TLR7TLR8 | |
| SCHEMBL15502400 | 0.74 | CYP2D6 (0.61) | TLR7TLR8 | |
| SCHEMBL24719138 | 0.74 | KCNH2 (0.37) | TLR7TLR8ALDH1A1 | |
| SCHEMBL15502335 | 0.73 | TLR7 (0.60) | TLR7TLR8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4059924-A1 | 2,4-DIAMINOQUINAZOLINE DERIVATIVES AND MEDICAL USES THEREOF | Janssen Sciences Ireland Unlimited Company (IE) | 2022-09-21 | — | — | EP | disclosed |