Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.64 |
| ▸ | BID | P55957 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TACR1 | P25103 | 4/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | ECE1 | P42892 | 2/20 | 0.57 |
| ▸ | TACR3 | P29371 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962313 | 0.90 | OPRD1 (0.61) | BCL2A1BIDKMT2ATACR1MAPT | |
| SCHEMBL31256544 | 0.89 | ACE (0.56) | BCL2A1BIDKMT2AACEECE1 | |
| SCHEMBL8999430 | 0.88 | MAPT (0.68) | BCL2A1BIDKMT2ATACR1MAPT | |
| SCHEMBL30051618 | 0.88 | ACE (0.61) | CTSLACEECE1TACR3 | |
| SCHEMBL9822759 | 0.88 | ACE (0.61) | CTSLACEECE1TACR3 | |
| SCHEMBL6019857 | 0.87 | CTSL (0.80) | BCL2A1BIDKMT2ATACR1CTSL | |
| SCHEMBL30052868 | 0.86 | KDM4E (0.60) | KMT2ACTSLMAPTACEECE1 | |
| SCHEMBL24933037 | 0.86 | CTSL (0.57) | TACR1CTSLACECTSSCTSK | |
| SCHEMBL6655016 | 0.86 | CTSL (0.57) | TACR1CTSLACECTSSCTSK | |
| SCHEMBL30052548 | 0.86 | CTSC (0.64) | CTSLACEECE1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079748-A1 | MODULATORS OF SORTILIN ACTIVITY | Insusense ApS (DK) | 2022-10-26 | — | — | EP | disclosed |