Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12522316 | 0.79 | TP53 (0.50) | TP53CYP4F2CYP4A11L3MBTL1HTT | |
| SCHEMBL15387041 | 0.78 | TP53 (0.44) | TP53CYP4F2CYP4A11L3MBTL1HTT | |
| SCHEMBL436002 | 0.78 | TP53 (0.44) | TP53CYP4F2CYP4A11L3MBTL1HTT | |
| SCHEMBL16127663 | 0.78 | TP53 (0.44) | TP53CYP4F2CYP4A11L3MBTL1HTT | |
| SCHEMBL15295187 | 0.76 | L3MBTL1 (0.45) | TP53CYP4F2CYP4A11L3MBTL1HTT | |
| SCHEMBL17545152 | 0.75 | TP53 (0.42) | TP53CYP4F2CYP4A11L3MBTL1HTT | |
| SCHEMBL4569273 | 0.75 | TP53 (0.42) | TP53CYP4F2CYP4A11L3MBTL1HTT | |
| SCHEMBL12448228 | 0.75 | TP53 (0.42) | TP53CYP4F2CYP4A11L3MBTL1HTT | |
| SCHEMBL24719151 | 0.75 | ALDH1A1 (0.44) | CYP4F2CYP4A11L3MBTL1HTTALDH1A1 | |
| SCHEMBL22064248 | 0.74 | KDM4E (0.32) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184975-A1 | PROCESS FOR THE PREPARATION OF A CYP11A1 INHIBITOR AND INTERMEDIATES THEREOF | ORION CORPORATION (FI) | 2022-09-09 | — | — | WO | disclosed |