Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182904 | 1.00 | FKBP1A (0.41) | FKBP1ARAB9AALDH1A1LMNATACR1 | |
| SCHEMBL2470362 | 0.86 | CYP2D6 (0.45) | FKBP1ARAB9AALDH1A1LMNATACR1 | |
| SCHEMBL2471483 | 0.84 | ALDH1A1 (0.55) | FKBP1ARAB9AALDH1A1TACR1TACR3 | |
| SCHEMBL2471735 | 0.84 | NPC1 (0.49) | FKBP1AALDH1A1LMNAEPHX1EPHX2 | |
| SCHEMBL2470205 | 0.84 | ALDH1A1 (0.51) | FKBP1ARAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL2467982 | 0.82 | MEN1 (0.42) | FKBP1ARAB9AALDH1A1LMNATACR1 | |
| SCHEMBL2467413 | 0.82 | ALDH1A1 (0.45) | FKBP1ARAB9AALDH1A1TAAR1POLB | |
| SCHEMBL2469565 | 0.82 | CYP2D6 (0.50) | ALDH1A1LMNACHRM5CHRM3TP53 | |
| SCHEMBL2471827 | 0.82 | ALDH1A1 (0.45) | FKBP1AALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL2467308 | 0.82 | KMT2A (0.42) | FKBP1ARAB9AALDH1A1LMNATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371366-A1 | Heterocyclo inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2011-10-05 | — | — | EP | disclosed |