SCHEMBL24720138

SCHEMBL24720138

CC[C@H](C)C(NC(=O)C1CNCCO1)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 9/20 0.46
CTSC P53634 7/20 0.40
ENPEP Q07075 2/20 0.37
CNR2 P34972 1/20 0.36
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21625333 0.81 SSTR4 (0.51) SSTR4CTSCKCNH2
SCHEMBL24720137 0.78 SSTR4 (0.39) SSTR4ENPEP
SCHEMBL24719229 0.78 SSTR4 (0.39) SSTR4ENPEP
SCHEMBL29516296 0.77 SSTR4 (0.55) SSTR4CTSCKCNH2
SCHEMBL20711876 0.77 SSTR4 (0.55) SSTR4CTSCKCNH2
SCHEMBL7598637 0.77 SSTR4 (0.50) SSTR4CTSC
SCHEMBL7598015 0.75 SSTR4 (0.48) SSTR4CTSC
SCHEMBL4956052 0.74 SSTR4 (0.52) SSTR4CTSC
SCHEMBL8860932 0.73 SSTR4 (0.52) SSTR4CTSC
SCHEMBL18664465 0.73 SSTR4 (0.52) SSTR4CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4079748-A1 MODULATORS OF SORTILIN ACTIVITY Insusense ApS (DK) 2022-10-26 EP disclosed