SCHEMBL24720137

SCHEMBL24720137

CC[C@H](C)[C@H](NC(=O)[C@H]1CNCCO1)C(=O)N[C@@H](CCC(C)(C)C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 3/20 0.39
ENPEP Q07075 17/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24719229 1.00 SSTR4 (0.39) SSTR4ENPEP
SCHEMBL27204937 0.86 NTSR2 (0.44)
SCHEMBL27172528 0.86 NTSR2 (0.44)
SCHEMBL27172559 0.86 NTSR2 (0.44)
SCHEMBL27204885 0.86 NTSR2 (0.44)
SCHEMBL24719032 0.80 ENPEP (0.34) ENPEP
SCHEMBL24718905 0.80 ENPEP (0.34) ENPEP
SCHEMBL24720138 0.78 SSTR4 (0.46) SSTR4ENPEP
SCHEMBL24718908 0.76 ENPEP (0.44) ENPEP
SCHEMBL30078226 0.75 MEN1 (0.40) ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217922-A1 MODULATORS OF SORTILIN ACTIVITY VESPER BIO APS (DK) 2024-07-04 US claimed
EP-4326742-A1 MODULATORS OF SORTILIN ACTIVITY Insusense ApS (DK) 2024-02-28 EP claimed
WO-2022223805-A1 MODULATORS OF SORTILIN ACTIVITY INSUSENSE ApS (DK) 2022-10-27 WO claimed
EP-4079748-A1 MODULATORS OF SORTILIN ACTIVITY Insusense ApS (DK) 2022-10-26 EP claimed
US-20240217922-A1 MODULATORS OF SORTILIN ACTIVITY VESPER BIO APS (DK) 2024-07-04 US disclosed
EP-4326742-A1 MODULATORS OF SORTILIN ACTIVITY Insusense ApS (DK) 2024-02-28 EP disclosed
WO-2022223805-A1 MODULATORS OF SORTILIN ACTIVITY INSUSENSE ApS (DK) 2022-10-27 WO disclosed
EP-4079748-A1 MODULATORS OF SORTILIN ACTIVITY Insusense ApS (DK) 2022-10-26 EP disclosed
EP-4079748-A1 MODULATORS OF SORTILIN ACTIVITY Insusense ApS (DK) 2022-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217922-A1 MODULATORS OF SORTILIN ACTIVITY SORT1, SCARB1, NPC1 SSTR4 1841/4885ENPEP 684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.