Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18177915 | 0.90 | HTT (0.47) | HTTHSD11B1KDM4EEPHX2ATM | |
| SCHEMBL16307931 | 0.77 | HTT (0.40) | HTTHSD11B1KDM4EEPHX2ATM | |
| SCHEMBL15922897 | 0.75 | TP53 (0.41) | HSD11B1KDM4EATMALDH1A1TSHR | |
| SCHEMBL24952353 | 0.73 | HRH3 (0.31) | MAPTKDM4EALDH1A1 | |
| SCHEMBL25043794 | 0.72 | — | — | |
| SCHEMBL1143530 | 0.68 | TP53 (0.41) | HSD11B1ATMTDP1ALDH1A1TSHR | |
| SCHEMBL19073248 | 0.65 | TP53 (0.36) | ATMALDH1A1TSHR | |
| SCHEMBL15922741 | 0.65 | TP53 (0.39) | HSD11B1ATMTDP1TSHR | |
| SCHEMBL11355878 | 0.65 | HSD11B1 (0.41) | HSD11B1ATMTDP1TSHR | |
| SCHEMBL455945 | 0.65 | TP53 (0.36) | KDM4EEPHX2ATMALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123991-A1 | TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS WITH INHIBITORS OF BET FAMILY BDII BROMODOMAIN | POSEIDON INNOVATION 1, INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024123999-A1 | TREATMENT OF GRAFT-VERSUS-HOST DISEASE WITH INHIBITORS OF BET FAMILY BDII BROMODOMAIN | POSEIDON INNOVATION 1, INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |