SCHEMBL2472082

SCHEMBL2472082

O=P(O)(Oc1ccccc1Cl)Oc1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.64
LMNA P02545 1/20 0.64
PTK2B Q14289 1/20 0.49
MAPK1 P28482 1/20 0.45
GPR84 Q9NQS5 1/20 0.44
PKM P14618 2/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
INPPL1 O15357 1/20 0.42
INPP5B P32019 1/20 0.42
INPP5A Q14642 1/20 0.42
HPGD P15428 2/20 0.41
TSHR P16473 1/20 0.41
SRC P12931 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
PDE3A Q14432 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30557968 1.00 SMN1; SMN2 (0.64) SMN1; SMN2LMNAPTK2BMAPK1GPR84
SCHEMBL9834120 0.91 LMNA (0.55) SMN1; SMN2LMNAPTK2BMAPK1GPR84
SCHEMBL28694226 0.90 SMN1; SMN2 (0.58) SMN1; SMN2LMNAPTK2BMAPK1GPR84
SCHEMBL29539956 0.88 LMNA (0.56) SMN1; SMN2LMNAPTK2BMAPK1GPR84
SCHEMBL9493718 0.88 SMN1; SMN2 (0.56) SMN1; SMN2LMNAPTK2BMAPK1GPR84
SCHEMBL10791070 0.88 SMN1; SMN2 (0.56) SMN1; SMN2LMNAPTK2BMAPK1GPR84
SCHEMBL2127225 0.87 LMNA (0.64) SMN1; SMN2LMNAPTK2BMAPK1PKM
Hydrochloric Acid SCHEMBL29188656 0.85 LMNA (0.62) SMN1; SMN2LMNAPTK2BMAPK1PKM
SCHEMBL9492467 0.85 SMN1; SMN2 (0.62) SMN1; SMN2LMNAPTK2BMAPK1PKM
SCHEMBL28853887 0.83 SMN1; SMN2 (0.60) SMN1; SMN2LMNAPTK2BMAPK1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116773728-A Method for determining organic phosphotriester and its precursor and metabolite in environment medium 南开大学 2023-09-19 CN claimed
CN-116773728-A Method for determining organic phosphotriester and its precursor and metabolite in environment medium 南开大学 2023-09-19 CN disclosed
CN-116322759-A Phospholipid compounds and uses thereof 吉利德科学公司 2023-06-23 CN disclosed
EP-1348716-B1 Aromatic polymer, method for producing the same and uses thereof SUMITOMO CHEMICAL CO (JP) 2011-10-12 EP disclosed
US-7285616-B2 Aromatic polymer, method for producing the same and uses thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-23 US disclosed
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
EP-0967674-B1 Solid polymer electrolytes HONDA MOTOR CO LTD (JP) 2006-03-22 EP disclosed
EP-1085034-B1 Proton conducting polymer, method for producing the same, solid polymer electrolyte and electrode HONDA MOTOR CO LTD (JP) 2005-12-28 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
EP-1085034-A1 Proton conducting polymer, method for producing the same, solid polymer electrolyte and electrode Honda Giken Kogyo Kabushiki Kaisha (JP) 2001-03-21 EP disclosed
US-6124060-A A POLY-2,5-BENZIMIDAZOLE DOPED WITH AN ACID IN WHICH A HYDROGEN ATOM OF AN INORGANIC ACID IS REPLACED WITH A PHENYL GROUP; MADE BY A WRINKLE-RESISTANT SOLUTION BLEND METHOD; LOW WATER ABSORPTION; NO DOPANT LEAKAGE WHEN PRESSED; FUEL CELLS HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2000-09-26 US disclosed
EP-1034177-A1 PROCESS FOR PRODUCING HALOGEN-CONTAINING PHOSPHATE ESTER DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-09-13 EP disclosed
WO-2000006584-A1 PROCESS FOR PRODUCING HALOGEN-CONTAINING PHOSPHATE ESTER DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2000-02-10 WO disclosed
EP-0967674-A1 Solid polymer electrolytes HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 1999-12-29 EP disclosed
US-5618934-A Boronic acid compound MERCK & CO., INC. (US) 1997-04-08 US disclosed
WO-1995031461-A1 PREPARATION OF 2-ARYL CARBAPENEMS MERCK & CO., INC. (US) 1995-11-23 WO disclosed
US-5442056-A Preparation of 2-aryl carbapenems MERCK & CO., INC. (US) 1995-08-15 US disclosed
US-4981773-A Method for stabilization of organic base substances against light FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
US-4138553-A 3-Methylene cephalosporanic acid derivatives and process for preparation thereof TEIJIN LIMITED (JP) 1979-02-06 US disclosed