Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | INPP5B | P32019 | 1/20 | 0.41 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426201 | 0.87 | INPPL1 (0.46) | SMN1; SMN2LMNAPTK2BPOLBGAA | |
| SCHEMBL2127225 | 0.85 | LMNA (0.64) | SMN1; SMN2LMNAPTK2BMAPK1PKM | |
| SCHEMBL2472082 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAPTK2BMAPK1PKM | |
| SCHEMBL30557968 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAPTK2BMAPK1PKM | |
| SCHEMBL29114274 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAPTK2BMAPK1POLB | |
| Hydrochloric Acid SCHEMBL29188656 | 0.83 | LMNA (0.62) | SMN1; SMN2LMNAPTK2BMAPK1PKM | |
| SCHEMBL1070126 | 0.83 | LMNA (0.67) | SMN1; SMN2LMNAPTK2BMAPK1PKM | |
| SCHEMBL30657703 | 0.83 | LMNA (0.67) | SMN1; SMN2LMNAPTK2BMAPK1PKM | |
| SCHEMBL29482311 | 0.83 | LMNA (0.67) | SMN1; SMN2LMNAPTK2BMAPK1PKM | |
| SCHEMBL1377760 | 0.83 | LMNA (0.67) | SMN1; SMN2LMNAPTK2BMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024658-A | Phospholipid terminal functionalized rare earth isoprene rubber and preparation method and application thereof | 海南天然橡胶产业集团股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-113924304-A | Tetrafunctional chemical probe and method for identifying target membrane proteins from living cells or living tissue using the same | 大塚制药株式会社 | 2022-01-11 | — | — | CN | disclosed |
| CN-109906230-B | Endosomolytic agent for gene therapy | UCB生物制药有限责任公司 | 2021-09-10 | — | — | CN | disclosed |
| US-5245069-A | Reacting a phosphoryl halide and a phenol in the presence of a dialkylaminopyridine and an arylphosphorodihalidate | MERCK & CO., INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0140953-A1 | O-HALOPHENYL O-ALKYL S-TERT-BUTYL PHOSPHOROTHIOATES | FMC Corporation (US) | 1985-05-15 | — | — | EP | disclosed |
| WO-1984004308-A1 | O-HALOPHENYL O-ALKYL S-TERT-BUTYL PHOSPHOROTHIOATES | FMC CORP (US) | 1984-11-08 | — | — | WO | disclosed |