Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 6/20 | 0.33 |
| ▸ | AXL | P30530 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 3/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475282 | 0.87 | AVPR1A (0.38) | AVPR2AVPR1AKCNH2TYRO3 | |
| Hydrochloric Acid SCHEMBL2472118 | 0.84 | HTR2C (0.34) | HTR2CFPR2PROKR1 | |
| SCHEMBL2346991 | 0.84 | SLC6A4 (0.32) | AVPR2AVPR1AKCNH2 | |
| SCHEMBL2472676 | 0.84 | GPR119 (0.36) | AVPR1A | |
| SCHEMBL2336166 | 0.83 | AVPR1A (0.31) | AVPR2AVPR1AKCNH2 | |
| SCHEMBL2472826 | 0.82 | AVPR1A (0.39) | AVPR2AVPR1AKCNH2 | |
| SCHEMBL2341614 | 0.82 | AVPR2 (0.32) | AVPR2AVPR1AKCNH2 | |
| SCHEMBL2339933 | 0.82 | IDH1 (0.31) | AVPR2AVPR1AKCNH2 | |
| SCHEMBL2563008 | 0.82 | AVPR1A (0.36) | AVPR2AVPR1AKCNH2 | |
| SCHEMBL2552411 | 0.81 | AVPR1A (0.34) | AVPR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370441-A1 | ARYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES FOR USE AS VASOPRESSIN VIA RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2011-10-05 | — | — | EP | disclosed |