Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549529 | 0.85 | AVPR2 (0.35) | AVPR1ATACR1KCNH2 | |
| SCHEMBL2563008 | 0.84 | AVPR1A (0.36) | AVPR1AKCNH2 | |
| Hydrochloric Acid SCHEMBL2544777 | 0.83 | AVPR1A (0.33) | AVPR1A | |
| SCHEMBL2346991 | 0.82 | SLC6A4 (0.32) | AVPR1ASLC6A4KCNH2 | |
| SCHEMBL2472145 | 0.81 | AVPR2 (0.34) | AVPR1AKCNH2 | |
| SCHEMBL2336166 | 0.81 | AVPR1A (0.31) | AVPR1AKCNH2 | |
| SCHEMBL2563323 | 0.81 | AVPR1A (0.33) | AVPR1A | |
| SCHEMBL2341614 | 0.80 | AVPR2 (0.32) | AVPR1AKCNH2 | |
| SCHEMBL2339933 | 0.80 | IDH1 (0.31) | AVPR1AKCNH2 | |
| SCHEMBL2556595 | 0.80 | CYP11B2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011120877-A1 | ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-10-06 | — | — | WO | disclosed |