Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662104 | 0.75 | CRBN (0.48) | CRBN | |
| SCHEMBL10290326 | 0.74 | NNMT (0.37) | CRBNDDB1NNMTSMYD3 | |
| SCHEMBL24722687 | 0.72 | CRBN (0.34) | CRBN | |
| SCHEMBL8351361 | 0.70 | ABL1 (0.54) | CRBNSMYD3 | |
| SCHEMBL23189285 | 0.69 | NNMT (0.38) | NNMTHTR2AHTR2CHTR2B | |
| SCHEMBL13662132 | 0.69 | KDM4E (0.36) | CRBNGAAKMT2A | |
| SCHEMBL22900729 | 0.68 | NNMT (0.34) | NNMT | |
| SCHEMBL24722688 | 0.68 | CRBN (0.33) | CRBN | |
| SCHEMBL91417 | 0.67 | NNMT (0.49) | NNMTHTR2AHTR2CHTR2B | |
| SCHEMBL24723535 | 0.66 | SMYD3 (0.36) | HTTCRBNDDB1POLBNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187329-A1 | FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-09-09 | — | — | WO | disclosed |