Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472360 | 1.00 | KMT2A (0.63) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL9705521 | 0.92 | KMT2A (0.65) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL9510921 | 0.91 | KMT2A (0.64) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL2474935 | 0.90 | LTA4H (0.58) | TACR1TP53 | |
| SCHEMBL2474927 | 0.90 | LTA4H (0.58) | TACR1TP53 | |
| SCHEMBL2473910 | 0.83 | ATM (0.55) | KMT2AMEN1 | |
| SCHEMBL2473913 | 0.83 | ATM (0.55) | KMT2AMEN1 | |
| SCHEMBL5381876 | 0.83 | KMT2A (0.61) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL27763768 | 0.83 | KMT2A (0.78) | KMT2AMEN1HCRTR1MAPTNPBWR1 | |
| SCHEMBL19051485 | 0.82 | KMT2A (0.78) | KMT2AMEN1HCRTR1MAPTNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| WO-2011107948-A2 | LIGANDS OF INSULIN DEGRADING ENZYME AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2011-09-09 | — | — | WO | disclosed |