Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 4/20 | 0.58 |
| ▸ | TACR1 | P25103 | 1/20 | 0.58 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.57 |
| ▸ | ITGAL | P20701 | 3/20 | 0.57 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474935 | 1.00 | LTA4H (0.58) | LTA4HALOX15ACETACR1ITGB2 | |
| SCHEMBL2472360 | 0.90 | KMT2A (0.63) | TACR1TP53 | |
| SCHEMBL2472353 | 0.90 | KMT2A (0.63) | TACR1TP53 | |
| SCHEMBL3388808 | 0.85 | ALOX15 (0.60) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL30919264 | 0.83 | ALOX15 (0.67) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL28046779 | 0.83 | ECE1 (0.71) | LTA4HALOX15ACEITGB2ICAM1 | |
| SCHEMBL11591677 | 0.83 | ECE1 (0.71) | LTA4HALOX15ACEITGB2ICAM1 | |
| SCHEMBL30936746 | 0.83 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL6426552 | 0.82 | ALOX15 (0.68) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL11369495 | 0.82 | ALOX15 (0.68) | ALOX15ACEITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |